On the reactive states of astrocytes in prion diseases

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Astrocytes in transmissible spongiform encephalopathies (prion diseases).

Astrocytosis is one of the hallmarks of neuropathology of transmissible spongiform encephalopathies (TSEs) or prion diseases. In this review, we summarize data on astrocytic reaction, including naturally occurring or experimentally induced TSEs. A particular form of astrocytic reaction is known as gliocytosis and it is typical for experimental scrapie in mouse or in hamsters. Also, astrocytes p...

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Human Prion Diseases in the United States

BACKGROUND Prion diseases are a family of rare, progressive, neurodegenerative disorders that affect humans and animals. The most common form of human prion disease, Creutzfeldt-Jakob disease (CJD), occurs worldwide. Variant CJD (vCJD), a recently emerged human prion disease, is a zoonotic foodborne disorder that occurs almost exclusively in countries with outbreaks of bovine spongiform encepha...

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ژورنال

عنوان ژورنال: Prion

سال: 2021

ISSN: 1933-6896,1933-690X

DOI: 10.1080/19336896.2021.1930852